On-Chip Control of DNA Immobilization and Hybridization with Nanosecond Electric Field Pulses


The application of on-chip single voltage pulses is used to achieve both temporal and spatial control of the biological reactions in DNA chips. Single square and sinusoidal voltage pulses with amplitudes between 0.1 and 5 V and durations between 20 ns and 10 ms are used to achieve specific DNA oligonucleotide probe covalent immobilization to a… (More)


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