• Published 2006

Omithine decarboxylase activity is a marker of premalignancy in longstanding Helicobacter pylori infection

@inproceedings{Patchett2006OmithineDA,
  title={Omithine decarboxylase activity is a marker of premalignancy in longstanding Helicobacter pylori infection},
  author={Stephen E. Patchett and Peter H Katelaris and Z. W. Zhang and Elspeth M Alstead and P. Domizio and G. William Farthing},
  year={2006}
}
Background-Longstanding Helicobacter pylori infection may increase the risk of developing gastric adenocarcinoma. The sequence of chronic active gastritis leading to gastritis with atrophy and subsequent intestinal metaplasia is thought to be a key step in gastric carcinogenesis. Ornithine decarboxylase (ODC) activity is increased in some pre-malignant gastrointestinal conditions and is essential for malignant transformation in vitro. Aims-To measure ODC activity in the antrum of H pyloni… CONTINUE READING

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