Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: results from a nationwide study.

@article{Lundin2001OmissionOH,
  title={Omission of histologic grading from clinical decision making may result in overuse of adjuvant therapies in breast cancer: results from a nationwide study.},
  author={Johan Lundin and Maria Lundin and Kaija A Holli and Vesa V. Kataja and Liisa Elomaa and Liisa H Pylkk{\"a}nen and Taina Turpeenniemi-Hujanen and Heikki Joensuu},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2001},
  volume={19 1},
  pages={28-36}
}
PURPOSE To investigate the influence of routinely performed histologic grading on breast cancer outcome prediction and patient selection for adjuvant therapy. PATIENTS AND METHODS The analysis is based on a cohort of 2,842 women diagnosed with breast cancer and comprising 91% of all breast cancers diagnosed in five defined geographical regions in Finland in 1991 through 1992. Data on clinicopathologic factors and follow-up were collected from hospital case records and national registries… CONTINUE READING