Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose.

@article{Tan2008Omentin1AN,
  title={Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose.},
  author={Bee Kang Tan and Raghu Adya and Syed Farhatullah and Kris C Lewandowski and Paul J O'Hare and Hendrik Lehnert and Harpal Randeva},
  journal={Diabetes},
  year={2008},
  volume={57 4},
  pages={801-8}
}
OBJECTIVE Polycystic ovary syndrome (PCOS) is associated with insulin resistance and obesity. Recent studies have shown that plasma omentin-1 levels decrease with obesity. Currently, no data exist on the relative expression and regulation of omentin-1 in adipose tissue of women with PCOS. The objective of this study was to assess mRNA and protein levels of omentin-1, including circulating omentin-1, in omental adipose tissue of women with PCOS and matched control subjects. Ex vivo and in vivo… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 94 extracted citations

Adipokines in human reproduction.

Hormone molecular biology and clinical investigation • 2015
View 4 Excerpts
Highly Influenced

Relationship among plasma adipokines, insulin and androgens level as well as biochemical glycemic and lipidemic markers with incidence of PCOS in women with normal BMI.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2012
View 5 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 19 references

A new mathematical model for relative quantification in real-time RT-PCR.

Nucleic acids research • 2001
View 8 Excerpts
Highly Influenced

Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue

A Schäffler, M Neumeier, +3 authors C. Büchler
Biochim Biophys Acta 1732:96-102, • 2005
View 1 Excerpt

Similar Papers

Loading similar papers…