Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle.

@article{Herbst2014Omega3SA,
  title={Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle.},
  author={Eric A. F. Herbst and Sabina Paglialunga and Christopher J Gerling and Jamie Whitfield and Kazutaka Mukai and Adrian Chabowski and George J. F. Heigenhauser and Lawrence Leon Spriet and Graham P Holloway},
  journal={The Journal of physiology},
  year={2014},
  volume={592 6},
  pages={1341-52}
}
Studies have shown increased incorporation of omega-3 fatty acids into whole skeletal muscle following supplementation, although little has been done to investigate the potential impact on the fatty acid composition of mitochondrial membranes and the functional consequences on mitochondrial bioenergetics. Therefore, we supplemented young healthy male subjects (n = 18) with fish oils [2 g eicosapentaenoic acid (EPA) and 1 g docosahexanoic acid (DHA) per day] for 12 weeks and skeletal muscle… CONTINUE READING
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