Corpus ID: 25273973

Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritis.

@article{Ruggiero2009Omega3PF,
  title={Omega-3 polyunsaturated fatty acids and immune-mediated diseases: inflammatory bowel disease and rheumatoid arthritis.},
  author={C. Ruggiero and F. Lattanzio and F. Lauretani and B. Gasperini and C. Andr{\'e}s-Lacueva and A. Cherubini},
  journal={Current pharmaceutical design},
  year={2009},
  volume={15 36},
  pages={
          4135-48
        }
}
Inflammation is part of the normal host response to infection and injury. However, inappropriate inflammation contributes to several diseases, including inflammatory bowel disease (IBD) and rheumatoid arthritis (RA). Both conditions are characterized by the excessive production of inflammatory cytokines, arachidonic acid (AA)-derived eicosanoids, and other inflammatory agents (e.g., reactive oxygen species, adhesion molecules). By virtue of their anti-inflammatory action, omega-3… Expand
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