Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes.

@article{Norris2007Omega3PF,
  title={Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes.},
  author={Jill M. Norris and Xiang Yin and Molly M Lamb and Katherine J. Barriga and Jennifer A. Seifert and Michelle Hoffman and Heather D. Orton and Anna E Baron and Michael J Clare-Salzler and H. Peter Chase and Nancy J. Szabo and Henry A. Erlich and George S. Eisenbarth and Marian J. Rewers},
  journal={JAMA},
  year={2007},
  volume={298 12},
  pages={
          1420-8
        }
}
CONTEXT Cod liver oil supplements in infancy have been associated with a decreased risk of type 1 diabetes mellitus in a retrospective study. OBJECTIVE To examine whether intakes of omega-3 and omega-6 fatty acids are associated with the development of islet autoimmunity (IA) in children. DESIGN, SETTING, AND PARTICIPANTS A longitudinal, observational study, the Diabetes Autoimmunity Study in the Young (DAISY), conducted in Denver, Colorado, between January 1994 and November 2006, of 1770… Expand
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TLDR
Neither vitamin D intake nor 25(OH)D levels throughout childhood were associated with the risk of islet autoimmunity (IA) or progression to type 1 diabetes in the population. Expand
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TLDR
Higher dietary GI and GL are not associated with IA development, but higher GI is associated with more rapid progression to type 1 diabetes in children with IA, perhaps due to increased demand on the beta-cell to release insulin. Expand
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TLDR
Serum biomarkers of milk and ruminant meat fat consumption are directly associated and linoleic acid is inversely associated with advanced β-cell autoimmunity in children with HLA-conferred susceptibility to type I diabetes. Expand
Food consumption and advanced β cell autoimmunity in young children with HLA-conferred susceptibility to type 1 diabetes: a nested case-control design.
TLDR
Intakes of cow milk and fruit and berry juices could be related to the development of advanced β cell autoimmunity. Expand
Maternal dietary fatty acid intake during pregnancy and the risk of preclinical and clinical type 1 diabetes in the offspring
TLDR
No conclusive associations between maternal fatty acid intake or food consumption during pregnancy and the development of type 1 diabetes in the offspring were detected. Expand
Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young
TLDR
The putative protective effect of n-3 fatty acids on IA may result from a complex interaction between intake and genetically controlled fatty acid desaturation. Expand
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