Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation.

@article{Mayer2002Omega3FA,
  title={Omega-3 fatty acids suppress monocyte adhesion to human endothelial cells: role of endothelial PAF generation.},
  author={Konstantin Mayer and Martina Merfels and Marion Muhly-Reinholz and Stephanie Gokorsch and Simone Rosseau and Juergen Lohmeyer and Nicole Schwarzer and Matthias Kruell and Norbert Suttorp and Friedrich Grimminger and Werner Seeger},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2002},
  volume={283 2},
  pages={H811-8}
}
Monocyte-endothelium interaction is a fundamental process in many acute and chronic inflammatory diseases. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are fish oil-derived alternative (omega-3) precursor fatty acids implicated in the suppression of inflammatory events. We investigated their influence on rolling and adhesion of monocytes to human umbilical vein endothelial cells (HUVEC) under laminar flow conditions in vitro. Exposure of HUVEC to tumor necrosis factor (TNF-alpha… CONTINUE READING
39 Citations
51 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 39 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Similar Papers

Loading similar papers…