Corpus ID: 897676

Omega-3 fatty acids have antidepressant activity in forced swimming test in Wistar rats.

@article{Lakhwani2007Omega3FA,
  title={Omega-3 fatty acids have antidepressant activity in forced swimming test in Wistar rats.},
  author={Lalit Lakhwani and Sudheer K Tongia and V. S. Pal and R. P. Agrawal and Prem Nyati and P. Phadnis},
  journal={Acta poloniae pharmaceutica},
  year={2007},
  volume={64 3},
  pages={
          271-6
        }
}

Lalit Lakhwani, Sudheer K Tongia, +3 authors P. Phadnis

Published 2007

Medicine

Acta poloniae pharmaceutica

Forced swimming test is used to induce a characteristic behavior of immobility in rats, which resembles depression in humans to some extent. We evaluated the effect of omega-3 fatty acids alone as well as compared it with the standard antidepressant therapy with fluoxetine in both acute and chronic studies. In both the studies, rats were divided into 4 groups and subjected to the following drug interventions - Group 1- control: Group 2- fluoxetine in dose of 10 mg/kg subcutaneously 23.5, 5 and… CONTINUE READING

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