Omega-3 fatty acids have antidepressant activity in forced swimming test in Wistar rats.

@article{Lakhwani2007Omega3FA,
  title={Omega-3 fatty acids have antidepressant activity in forced swimming test in Wistar rats.},
  author={Lalit Lakhwani and Sudheer K Tongia and Veerendra S Pal and Rajendra Prasad Agrawal and Prem Nyati and Pradeep Phadnis},
  journal={Acta poloniae pharmaceutica},
  year={2007},
  volume={64 3},
  pages={271-6}
}

• Lalit Lakhwani, Sudheer K Tongia, +3 authors Pradeep Phadnis
• Published 2007 in Acta poloniae pharmaceutica

Forced swimming test is used to induce a characteristic behavior of immobility in rats, which resembles depression in humans to some extent. We evaluated the effect of omega-3 fatty acids alone as well as compared it with the standard antidepressant therapy with fluoxetine in both acute and chronic studies. In both the studies, rats were divided into 4 groups and subjected to the following drug interventions - Group 1- control: Group 2- fluoxetine in dose of 10 mg/kg subcutaneously 23.5, 5 and… CONTINUE READING

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