Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-β42 by human microglia and decrease inflammatory markers.

@article{Hjorth2013Omega3FA,
  title={Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-β42 by human microglia and decrease inflammatory markers.},
  author={Erik Hjorth and Mingqin Zhu and Veronica Cort{\'e}s Toro and Inger Vedin and Jan Palmblad and Tommy E Cederholm and Yvonne Freund-Levi and Gerd Fax{\'e}n-Irving and Lars-Olof Wahlund and Hans Basun and Maria Eriksdotter and Marianne Schultzberg},
  journal={Journal of Alzheimer's disease : JAD},
  year={2013},
  volume={35 4},
  pages={697-713}
}
The use of supplements with omega-3 (ω3) fatty acids (FAs) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) is widespread due to proposed beneficial effects on the nervous and cardiovascular systems. Many effects of ω3 FAs are believed to be caused by down-regulation and resolution of inflammation. Alzheimer's disease (AD) is associated with inflammation mediated by microglia and astrocytes, and ω3 FAs have been proposed as potential treatments for AD. The focus of the present… CONTINUE READING

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