Omega-3 fatty acids' supplementation in Alzheimer's disease: A systematic review

@article{Canhada2018Omega3FA,
  title={Omega-3 fatty acids' supplementation in Alzheimer's disease: A systematic review},
  author={Scheine Leite Canhada and Kamila Castro and Ingrid Dalira Schweigert Perry and Vivian Cristine Luft},
  journal={Nutritional Neuroscience},
  year={2018},
  volume={21},
  pages={529 - 538}
}
Introduction: Alzheimer's disease (AD) is a neurodegeneration disorder characterized by progressive impairments of memory, language, reasoning, and other cognitive functions. Evidence suggests that omega-3 fatty acids may act as a possible protection factor in AD. Objective: To evaluate the results available in the literature involving omega-3 fatty acids supplementation and its effect on cognitive function in AD patients. Methods: A systematic review of MEDLINE (from PubMed), Excerpta Medica… 
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TLDR
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TLDR
The combination of ω-3+LA slowed cognitive and functional decline in AD over 12 months and the combination of omega-3 fatty acids plus alpha-lipoic acid as a potential treatment in AD is warranted.
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TLDR
There was no evidence of a benefit from omega-3 PUFAs on cognitive function when measured at six months with the Alzheimer's Disease Assessment Scale - Cognitive subscale, and the overall quality of evidence for most of the outcomes was high.
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TLDR
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TLDR
This review will focus on epidemiological evidence investigating the relationship between nutrition and AD, focusing particularly on the roles of dietary fats and antioxidants.
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