Oltipraz treatment in experimental schistosomiasis mansoni: VI. Effect of high dose oral therapy on alkaline phosphatase level in the intestines of infected mice.


Extraction of alkaline phosphatase (AP) from the tissues of small intestines of mice experimentally infected with the Egyptian strain of S. mansoni before and after oltipraz treatment was carried out. The drug was given in a single oral dose of 500 mg/kg body weight. The results obtained revealed that the drug led to significant reduction in the AP mean… (More)