Olprinone: a phosphodiesterase III inhibitor with positive inotropic and vasodilator effects.

@article{Mizushige2002OlprinoneAP,
  title={Olprinone: a phosphodiesterase III inhibitor with positive inotropic and vasodilator effects.},
  author={Katsufumi Mizushige and Takashi Ueda and Kazushi Yukiiri and Hitoshi Suzuki},
  journal={Cardiovascular drug reviews},
  year={2002},
  volume={20 3},
  pages={163-74}
}
Olprinone is a newly developed phosphodiesterase III inhibitor characterized by several properties. First, olprinone has positive inotropic and vasodilator actions and improves myocardial mechanical efficiency. Second, olprinone augments cerebral blood flow by a direct vasodilatory effect on cerebral arteries. The cerebrovascular reactivity to olprinone is… CONTINUE READING