Olmesartan medoxomil: influence of age, renal and hepatic function on the pharmacokinetics of olmesartan medoxomil.

@article{Bergmann2001OlmesartanMI,
  title={Olmesartan medoxomil: influence of age, renal and hepatic function on the pharmacokinetics of olmesartan medoxomil.},
  author={Klaus von Bergmann and Petra Laeis and K. P{\"u}chler and Thomas Sudhop and Lee R Schwocho and Laura Gonz{\'a}lez},
  journal={Journal of hypertension. Supplement : official journal of the International Society of Hypertension},
  year={2001},
  volume={19 1},
  pages={S33-40}
}
Olmesartan medoxomil was rapidly absorbed and converted to olmesartan in elderly hypertensive patients, and in patients with renal and hepatic dysfunction. No olmesartan medoxomil itself was detected in plasma. Pharmacokinetic steady state was reached within the first few days after oral dosing. In elderly (65-75 years old), after 80 mg olmesartan medoxomil once daily, and very elderly (> or = 75 years old) hypertensive patients after 10 mg daily, steady-state Cmax and area under the curve (AUC… CONTINUE READING