Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats.

@article{Omagari2010OliveLE,
  title={Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats.},
  author={Katsuhisa Omagari and Shigeko Kato and Koichi Tsuneyama and Hideki Hatta and Miki Sato and Mizuho Hamasaki and Yukiko Sadakane and Takehiro Tashiro and Mitsue Fukuhata and Yuji Miyata and Shizuka Tamaru and Kazunari Tanaka and Masatoshi Mune},
  journal={Pathology},
  year={2010},
  volume={42 1},
  pages={66-72}
}
AIMS Oxidative stress may play an important role in the pathogenesis of non-alcoholic steatohepatitis (NASH). Oleuropein, the active constituent of olive leaf, possesses anti-oxidant, hypoglycaemic, and hypolipidaemic activities. We aimed to investigate the preventive effects of olive leaf extract on hepatic fat accumulation in a rat model of NASH. METHODS Spontaneously hypertensive/NIH-corpulent rats were fed a diet of AIN-93G with or without olive leaf extract (500, 1000, 2000 mg/kg diet… CONTINUE READING