Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.

@article{Kelleher2003OligosaccharyltransferaseIT,
  title={Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.},
  author={Daniel J. Kelleher and Denise Karaoglu and Elisabet C Mandon and Reid Gilmore},
  journal={Molecular cell},
  year={2003},
  volume={12 1},
  pages={101-11}
}
Oligosaccharyltransferase (OST) is an integral membrane protein that catalyzes N-linked glycosylation of nascent proteins in the lumen of the endoplasmic reticulum. Although the yeast OST is an octamer assembled from nonhomologous subunits (Ost1p, Ost2p, Ost3p/Ost6p, Ost4p, Ost5p, Wbp1p, Swp1p, and Stt3p), the composition of the vertebrate OST was less well defined. The roles of specific OST subunits remained enigmatic. Here we show that genomes of most multicellular eukaryotes encode two… CONTINUE READING
68 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 68 extracted citations

Similar Papers

Loading similar papers…