Oligoribonucleotide initiators for herpes simplex virus DNA synthesis in vivo and in vitro.

@article{Mueller1979OligoribonucleotideIF,
  title={Oligoribonucleotide initiators for herpes simplex virus DNA synthesis in vivo and in vitro.},
  author={Walter E. Mueller and Rudolf Karl Zahn and Josef Arendes and Dietrich Falke},
  journal={Virology},
  year={1979},
  volume={98 1},
  pages={
          200-10
        }
}
Abstract Replicating herpes simplex virus (HSV) DNA, labeled with [ 3 H]thymidine or [ 3 H]uridine, was isolated from infected primary rabbit kidney cells. Nascent DNA strands are covalently linked to oligoribonucleotide stretches. The chain length of this RNA segment amounts to approximately 36 nucleotides wich are located at the terminus of the replicating DNA. The extent of RNA initiator synthesis seems to be closely correlated with the rate of HSV-DNA synthesis. The half life of the RNA… CONTINUE READING

Citations

Publications citing this paper.