Oligopeptidase A is required for normal phage P22 development.

  title={Oligopeptidase A is required for normal phage P22 development.},
  author={C A Conlin and Eric R. Vimr and Charles G. Miller},
  journal={Journal of bacteriology},
  volume={174 18},
The opdA gene of Salmonella typhimurium encodes an endoprotease, oligopeptidase A (OpdA). Strains carrying opdA mutations were deficient as hosts for phage P22. P22 and the closely related phages L and A3 formed tiny plaques on an opdA host. Salmonella phages 9NA, KB1, and ES18.h1 were not affected by opdA mutations. Although opdA strains displayed normal doubling times and were infected by P22 as efficiently as opdA+ strains, the burst size of infectious particles from an opdA host was less… CONTINUE READING

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