Oligonucleotide microarray: a new rapid method for screening the 23S rRNA gene of Helicobacter pylori for single nucleotide polymorphisms associated with clarithromycin resistance.

@article{Chen2008OligonucleotideMA,
  title={Oligonucleotide microarray: a new rapid method for screening the 23S rRNA gene of Helicobacter pylori for single nucleotide polymorphisms associated with clarithromycin resistance.},
  author={Shaohua Chen and Youming Li and Chaohui Yu},
  journal={Journal of gastroenterology and hepatology},
  year={2008},
  volume={23 1},
  pages={126-31}
}
BACKGROUND AND AIM Resistance to antibiotics in Helicobacter pylori is increasing and becoming a serious problem in eradication treatment. Resistance of H. pylori to clarithromycin has been found to be associated with 2142 A-to-G, 2143 A-to-G and 2182 C-to-T point mutations in the 23S rRNA gene. Thus, the purpose of the present study was to develop a new… CONTINUE READING