Oligonucleotide-based Analysis of Differentially Expressed Genes in Hippocampus of Transgenic Mice Expressing NSE-controlled APPsw

@article{Jee2006OligonucleotidebasedAO,
  title={Oligonucleotide-based Analysis of Differentially Expressed Genes in Hippocampus of Transgenic Mice Expressing NSE-controlled APPsw},
  author={Seung Wan Jee and Jung Cho and Chuel Kyu Kim and Dae Youn Hwang and Sun Bo Shim and Su Hae Lee and Ji Soon Sin and Jin Hee Park and Yang Seok Kim and Soo Young Choi and Yong Kyu Kim},
  journal={Neurochemical Research},
  year={2006},
  volume={31},
  pages={1035-1044}
}
The complexity of Alzheimer’s disease (AD) has made it difficult to examine its underlying mechanisms. A gene microarray offers a solution to the complexity through parallel analysis of most of the genes expressed in the hippocampal tissues from AD-transgenic and age-matched control littermates. This study examined the potential effect of APPsw over-expression on the modulation of genes for AD. To accomplish this, an oligonucleotide array was used with the large-scale screening of the… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
5 Citations
14 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 14 references

Similar Papers

Loading similar papers…