Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells.

@article{Jain2001OligomerizationOG,
  title={Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells.},
  author={Renu K Jain and Paul B. M. Joyce and Miguel Molinete and Philippe A. Halban and Sven-Ulrik Gorr},
  journal={The Biochemical journal},
  year={2001},
  volume={360 Pt 3},
  pages={645-9}
}
Green fluorescent protein (GFP) is used extensively as a reporter protein to monitor cellular processes, including intracellular protein trafficking and secretion. In general, this approach depends on GFP acting as a passive reporter protein. However, it was recently noted that GFP oligomerizes in the secretory pathway of endocrine cells. To characterize this oligomerization and its potential role in GFP transport, cytosolic and secretory forms of enhanced GFP (EGFP) were expressed in GH4C1 and… CONTINUE READING

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