Oligomerization and pore formation of a sphingomyelin-specific toxin, lysenin.

@article{YamajiHasegawa2003OligomerizationAP,
  title={Oligomerization and pore formation of a sphingomyelin-specific toxin, lysenin.},
  author={Akiko Yamaji-Hasegawa and Asami Makino and Takeshi Baba and Yukiko Senoh and Hiromi Kimura-Suda and Satoshi Sato and Nobuo Terada and Shinichi Ohno and Etsuko Kiyokawa and Masato Umeda and Toshihide Kobayashi},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 25},
  pages={22762-70}
}
Lysenin is a novel protein derived from coelomic fluid of the earthworm Eisenia foetida, which specifically recognizes sphingomyelin and induces cytolysis. The mechanism underlying lysenin-induced cell lysis has not been clarified. In this report we studied the interaction of lysenin with red blood cells as well as artificial liposomes. Our results showed… CONTINUE READING