Oligomeric assembly and interactions within the human RuvB-like RuvBL1 and RuvBL2 complexes.

@article{Niewiarowski2010OligomericAA,
  title={Oligomeric assembly and interactions within the human RuvB-like RuvBL1 and RuvBL2 complexes.},
  author={Andrew Niewiarowski and Alison Sylvia Bradley and Jayesh Gor and Adam R. McKay and Stephen J Perkins and Irina R. Tsaneva},
  journal={The Biochemical journal},
  year={2010},
  volume={429 1},
  pages={113-25}
}
The two closely related eukaryotic AAA+ proteins (ATPases associated with various cellular activities), RuvBL1 (RuvB-like 1) and RuvBL2, are essential components of large multi-protein complexes involved in diverse cellular processes. Although the molecular mechanisms of RuvBL1 and RuvBL2 function remain unknown, oligomerization is likely to be important for their function together or individually, and different oligomeric forms might underpin different functions. Several experimental… CONTINUE READING