Oligodendroglial cell death induced by oxygen radicals and its protection by catalase

@article{Kim1991OligodendroglialCD,
  title={Oligodendroglial cell death induced by oxygen radicals and its protection by catalase},
  author={Y. Kim and S. Kim},
  journal={Journal of Neuroscience Research},
  year={1991},
  volume={29}
}
  • Y. Kim, S. Kim
  • Published 1991
  • Biology, Medicine
  • Journal of Neuroscience Research
The cytotoxic effects of oxygen radicals have been studied in enriched population of mature bovine oligodendrocytes in culture. Oxygen radicals were generated enzymatically by glucose and glucose oxidase, and hypoxanthine and xanthine oxidase combinations. Cytotoxicity was assessed by trypan blue exclusion and percentage lactate dehydrogenase release into the culture media. Incubation of bovine oligodendrocytes with these oxygen radical‐generating systems for 4 hr resulted in significant cell… Expand
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Overexpression of superoxide dismutase and catalase in immortalized neural cells: toxic effects of hydrogen peroxide
Oxygen radical‐induced neurotoxicity in spinal cord neuron cultures
Peroxide‐scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress
Delayed oligodendrocyte degeneration induced by brief exposure to hydrogen peroxide
Peroxynitrite‐induced oligodendrocyte toxicity is not dependent on poly(ADP‐ribose) polymerase activation
Astrocytes and catalase prevent the toxicity of catecholamines to oligodendrocytes
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References

SHOWING 1-10 OF 32 REFERENCES
Hydrogen peroxide causes the fatal injury to human fibroblasts exposed to oxygen radicals.
Liposome-mediated augmentation of catalase in alveolar type II cells protects against H2O2 injury.
Suppression of experimental autoimmune neuritis by the oxygen radical scavengers superoxide dismutase and catalase
Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.
Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity
Effects of antioxidants on oxidant-induced sister chromatid exchange formation.
Effects of culture duration on hydrogen peroxide-induced hepatocyte toxicity.
Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide.
Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage.
Appearance of Superoxide Anion Radical in Cerebral Extracellular Space during Increased Prostaglandin Synthesis in Cats
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