Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ-opioid- and nociceptin/orphanin FQ receptors in cell development: implications for drug addiction treatment during pregnancy.

@article{Eschenroeder2012OligodendrocyteRT,
  title={Oligodendrocyte responses to buprenorphine uncover novel and opposing roles of μ-opioid- and nociceptin/orphanin FQ receptors in cell development: implications for drug addiction treatment during pregnancy.},
  author={Andrew C Eschenroeder and Allison A Vestal-Laborde and Emilse S Sanchez and Susan E. Robinson and Carmen Sato-Bigbee},
  journal={Glia},
  year={2012},
  volume={60 1},
  pages={125-36}
}
Although the classical function of myelin is the facilitation of saltatory conduction, this membrane and the oligodendrocytes, the cells that make myelin in the central nervous system (CNS), are now recognized as important regulators of plasticity and remodeling in the developing brain. As such, oligodendrocyte maturation and myelination are among the most vulnerable processes along CNS development. We have shown previously that rat brain myelination is significantly altered by buprenorphine… CONTINUE READING