Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord.

@article{Wolswijk2002OligodendrocytePC,
  title={Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord.},
  author={Guus Wolswijk},
  journal={Brain : a journal of neurology},
  year={2002},
  volume={125 Pt 2},
  pages={338-49}
}
Lesions appearing in the CNS of patients in the chronic phase of the inflammatory, demyelinating disease multiple sclerosis often fail to repair, resulting in neurological dysfunction. This failure of remyelination appears, in many cases, to be due not to the destruction of the local oligodendrocyte precursor population, a source for new myelin-forming cells, but to the failure of the precursor cells to proliferate and differentiate, at least in brain lesions. The spinal cord is also a… CONTINUE READING