Oligodendrocyte precursor cells: reactive cells that inhibit axon growth and regeneration.

@article{Chen2002OligodendrocytePC,
  title={Oligodendrocyte precursor cells: reactive cells that inhibit axon growth and regeneration.},
  author={Z. J. Chen and Micheal Negra and Angela Levine and Yvonne M Ughrin and Joel M. Levine},
  journal={Journal of neurocytology},
  year={2002},
  volume={31 6-7},
  pages={481-95}
}
Oligodendrocyte precursor cells (OPCs) are a newly recognized glial component of the adult central nervous system of unknown function. Antibodies against the NG2 chondroitin sulfate proteoglycan have been useful tools to identify these cells in intact tissue. Here we review studies that show that OPCs react to several types of experimentally induced brain injury. Injury stimulates OPCs to re-enter the cell cycle, divide, and accumulate at the site of damage. OPCs, together with microglia and… CONTINUE READING

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