Oligodendrocyte maturation and myelin gene expression in PDGF-treated cultures from rat cerebral white matter.

Abstract

Myelination in the CNS is accompanied by the differentiation of oligodendrocytes as well as the coordinate expression of a group of myelin-specific genes, including those encoding proteolipid protein and myelin basic protein. In order to compare the timing of the onset of myelin gene expression with the known sequence of oligodendrocyte maturation, we… (More)

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