Oligochitosan stimulated phagocytic activity of macrophages from blunt snout bream (Megalobrama amblycephala) associated with respiratory burst coupled with nitric oxide production.

@article{Liu2014OligochitosanSP,
  title={Oligochitosan stimulated phagocytic activity of macrophages from blunt snout bream (Megalobrama amblycephala) associated with respiratory burst coupled with nitric oxide production.},
  author={Lichun Liu and Yang Zhou and Xiaoheng Zhao and Hong Wang and Li Wang and Gailing Yuan and Muhammad Rafiq Asim and Weimin Wang and Lingbing Zeng and Xiaoling Liu and Li Lin},
  journal={Developmental and comparative immunology},
  year={2014},
  volume={47 1},
  pages={17-24}
}
The immunostimulating effects of oligochitosan have been proven in several fish, however, the mechanisms underlying the stimulation are not characterized. In the present study, the effects of oligochitosan were investigated using macrophages isolated from blunt snout bream (Megalobrama amblycephala). The results showed that the phagocytic activity of the macrophages was enhanced by the addition of oligochitosan in vitro and in vivo. The two of the most important antimicrobial pathways of… CONTINUE READING