Olfactory uptake of manganese requires DMT1 and is enhanced by anemia.

@article{Thompson2007OlfactoryUO,
  title={Olfactory uptake of manganese requires DMT1 and is enhanced by anemia.},
  author={Khristy J. Thompson and Ramon M Molina and Thomas C. Donaghey and James E Schwob and Joseph D. Brain and Marianne Wessling-Resnick},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2007},
  volume={21 1},
  pages={223-30}
}
Manganese, an essential nutrient, can also elicit toxicity in the central nervous system (CNS). The route of exposure strongly influences the potential neurotoxicity of manganese-containing compounds. Recent studies suggest that inhaled manganese can enter the rat brain through the olfactory system, but little is known about the molecular factors involved… CONTINUE READING