Olfactory signals mediate social buffering of conditioned fear responses in male rats

@article{Takahashi2013OlfactorySM,
  title={Olfactory signals mediate social buffering of conditioned fear responses in male rats},
  author={Yuji K Takahashi and Y. Kiyokawa and Y. Kodama and S. Arata and Y. Takeuchi and Y. Mori},
  journal={Behavioural Brain Research},
  year={2013},
  volume={240},
  pages={46-51}
}
In social animals, the presence of an affiliative conspecific alleviates acute stress responses, and this is called social buffering. We previously reported that social buffering mitigates the fear responses of male rats to auditory conditioned stimuli that had been paired with foot shocks. Subsequent studies revealed that signals that are perceived by the main olfactory epithelium are important for social buffering. Because olfactory signals are the signal perceived by the main olfactory… Expand
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The present results suggest that social buffering enhances extinction of conditioned fear responses, as well as hypothalamic-pituitary-adrenal axis activation, elicited by an auditory conditioned stimulus (CS). Expand
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It is concluded that social buffering can ameliorate conditioned fear responses in female rats by reducing the intensity of the rats' fear responses to the CS or their degree of vigilance due to the presence of a conspecific animal. Expand
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TLDR
The present results provide direct evidence for the existence of social buffering of conditioned fear responses in male rats and suggest that the presence of a conspecific suppressed the behavioral responses and HPA axis activation to the CS. Expand
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TLDR
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Social buffering ameliorates conditioned fear responses in the presence of an auditory conditioned stimulus.
TLDR
It is indicated that social buffering ameliorates conditioned fear responses in the presence of an auditory CS when the duration and frequency of fear responses was measured. Expand
Social buffering suppresses fear-associated activation of the lateral amygdala in male rats: behavioral and neurophysiological evidence
TLDR
The results provide the first electrophysiological evidence that social buffering suppresses CS-induced activation in the LA, which consequently reduces conditioned fear responses. Expand
The lateral intercalated cell mass of the amygdala is activated during social buffering of conditioned fear responses in male rats
TLDR
It is proposed that the AOP indirectly suppresses the lateral amygdala by activating the lITC, which was activated during social buffering in a fear-conditioned Wistar subject rat. Expand
Social buffering enhances extinction of conditioned fear responses by reducing corticosterone levels in male rats
TLDR
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The strain of an accompanying conspecific affects the efficacy of social buffering in male rats
TLDR
It is concluded that strains of an accompanying conspecific can affect the efficacy of social buffering in rats, and the difference in origin, rather than the inbred or outbred status of the associate rat, seemed to account for the lack of socialbuffering induced by the F344 rats. Expand
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References

SHOWING 1-10 OF 44 REFERENCES
Main olfactory system mediates social buffering of conditioned fear responses in male rats
TLDR
It is concluded that the main olfactory system is essential for the social buffering but does not require physical contact between the dyad, and Lesioning of the main Olfactory epithelium by injection of ZnSO4 intranasally also abolished socialbuffering. Expand
The neural pathway underlying social buffering of conditioned fear responses in male rats
TLDR
It is suggested that the pmOP links the main olfactory blub to the amygdala and enables social buffering of conditioned fear responses and provides the first comprehensive picture of the neural pathway underlying the socialbuffering phenomenon. Expand
Two types of social buffering differentially mitigate conditioned fear responses
TLDR
It is demonstrated that two types of social buffering differentially relieve conditioned fear responses, by influencing different neural pathways in the amygdala. Expand
Social modeling of conditioned fear in mice by non-fearful conspecifics
TLDR
These findings identify an important social buffering process serving to prevent a lasting induction of fear in response to isolated, moderately intense stressful events. Expand
Predator odor-induced conditioned fear involves the basolateral and medial amygdala.
TLDR
Results show that theBLA participates in the conditioned and unconditioned cat odor stimulus association that underlies fear memory, underscore a novel role of the MeA in predator odor contextual conditioning, and demonstrate different roles of the BLA and Mea in modulating consolidation and retrieval of predator odor fear memory. Expand
Predator odor as an unconditioned fear stimulus in rats: elicitation of freezing by trimethylthiazoline, a component of fox feces.
: Four experiments tested whether an odor from a rat predator can unconditionally elicit a fear response in rats. In a large chamber, rats displayed fear-related behaviors to trimethylthiazolineExpand
Disrupting basolateral amygdala function impairs unconditioned freezing and avoidance in rats
TLDR
It is reported that both temporary inactivation (lidocaine) and permanent excitotoxic (NMDA) lesions of the BLC impair the unconditioned freezing and avoidance behaviours of rats in response to a novel fear‐eliciting stimulus, a ball of cat hair. Expand
Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety
TLDR
Data will be reviewed using the acoustic startle reflex in rats and humans based on attempts to operationally define fear vs anxiety, finding that symptoms of clinical anxiety are better detected in sustained rather than phasic fear paradigms. Expand
Mapping the neural circuit activated by alarm pheromone perception by c-Fos immunohistochemistry
TLDR
It is suggested that the perception of the alarm pheromone is related to stress-responsive brains structures, including the hypothalamus and brainstem, as well as to the amygdaloid nuclei. Expand
Partner's stress status influences social buffering effects in rats.
TLDR
It is suggested that the social buffering effect depends on the stress status of the accompanying conspecific animal. Expand
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