Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.

@article{Cui2013OlfactoryR5,
  title={Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas.},
  author={Tao Cui and Apostolos Tsolakis and Su-Chen Li and Janet L. Cunningham and Thomas Lind and Kjell {\"O}berg and Valeria Giandomenico},
  journal={European journal of endocrinology},
  year={2013},
  volume={168 2},
  pages={253-61}
}
OBJECTIVE Late diagnosis hinders proper management of small intestine neuroendocrine carcinoma (SI-NEC) patients. The olfactory receptor, family 51, subfamily E, member 1 (OR51E1) has been reported as a potential novel SI-NEC marker, without protein expression recognition. Thus, we further studied whether the encoded protein may be a novel SI-NEC clinical biomarker. DESIGN OR51E1 coding sequence was cloned using total RNA from SI-NEC patient specimens. Quantitative real-time PCR analysis… CONTINUE READING