Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals.

@article{Lin2007OlfactoryNE,
  title={Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals.},
  author={Weihong Lin and Robert F Margolskee and Gerald Donnert and Stefan W Hell and Diego Restrepo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 7},
  pages={2471-6}
}
Olfactory sensory neurons (OSNs) in the main olfactory epithelium respond to environmental odorants. Recent studies reveal that these OSNs also respond to semiochemicals such as pheromones and that main olfactory input modulates animal reproduction, but the transduction mechanism for these chemosignals is not fully understood. Previously, we determined that responses to putative pheromones in the main olfactory system were reduced but not eliminated in mice defective for the canonical cAMP… CONTINUE READING