Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.

@article{Ennis2006OlfactoryNM,
  title={Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.},
  author={Matthew Ennis and Mingyan Zhu and Thomas Heinbockel and Abdallah M. Hayar},
  journal={Journal of neurophysiology},
  year={2006},
  volume={95 4},
  pages={2233-41}
}
The group I metabotropic glutamate receptor (mGluR) subtype, mGluR1, is highly expressed on the apical dendrites of olfactory bulb mitral cells and thus may be activated by glutamate released from olfactory nerve (ON) terminals. Previous studies have shown that mGluR1 agonists directly excite mitral cells. In the present study, we investigated the involvement of mGluR1 in ON-evoked responses in mitral cells in rat olfactory bulb slices using patch-clamp electrophysiology. In voltage-clamp… CONTINUE READING