Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia

@article{Rupp2005OlfactoryFA,
  title={Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia},
  author={Claudia I. Rupp and Walter Wolfgang Fleischhacker and Georg Kemmler and Christian Kremser and Robert M. Bilder and Sergei Mechtcheriakov and Philip R. Szeszko and Thomas Walch and Arne W. Scholtz and Martina Klimbacher and Claudia Maier and Gudrun Albrecht and Theresia Lechner-Schoner and Stefan Felber and Hartmann Hinterhuber},
  journal={Schizophrenia Research},
  year={2005},
  volume={74},
  pages={149-161}
}
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A subregion-specific OFC grey matter volume deficit in patients with schizophrenia was demonstrated, which was independent of OFC sulcogyral pattern and associated with a longer duration of illness and greater formal thought disorder.
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Size matters - The olfactory bulb as a marker for depression.
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TLDR
Findings indicate that olfactory deficits extend beyond measures of odor identification in FEP with greater deficits observed in schizophrenia-related subgroups of psychosis.
Automated Immunohistochemical Analysis of the Orbitofrontal Cortex in Patients with Schizophrenia, Bipolar Disorder and Major Depressive Disorder
TLDR
The entire OFC in patients with MDD, BP and SCZ was analyzed using a novel approach with layer-specific immunohistochemical markers and an automated counting protocol, suggesting that inconsistencies in the literature may arise from sampling only small areas of the cortex in a limited number of subjects.
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