Olfactory dysfunction in the pathophysiological continuum of dementia
@article{Bathini2019OlfactoryDI, title={Olfactory dysfunction in the pathophysiological continuum of dementia}, author={P. Bathini and E. Brai and L. A. Auber}, journal={Ageing Research Reviews}, year={2019}, volume={55} }
Sensory capacities like smell, taste, hearing, vision decline with aging, but increasing evidence show that sensory dysfunctions are one of the early signs diagnosing the conversion from physiological to pathological brain state. Smell loss represents the best characterized sense in clinical practice and is considered as one of the first preclinical signs of Alzheimer's and Parkinson's disease, occurring a decade or more before the onset of cognitive and motor symptoms. Despite the numerous… Expand
Topics from this paper
14 Citations
Why dizziness is likely to increase the risk of cognitive dysfunction and dementia in elderly adults.
- Medicine
- The New Zealand medical journal
- 2020
- PDF
Functional Alterations in the Olfactory Neuronal Circuit Occur before Hippocampal Plasticity Deficits in the P301S Mouse Model of Tauopathy: Implications for Early Diagnosis and Translational Research in Alzheimer’s Disease
- Biology, Medicine
- International journal of molecular sciences
- 2020
- 1
- PDF
The additive effect of late-life depression and olfactory dysfunction on the risk of dementia was mediated by hypersynchronization of the hippocampus/fusiform gyrus
- Medicine
- Translational Psychiatry
- 2021
- PDF
Olfactory impairment and the risk of cognitive decline and dementia in older adults: a meta-analysis.
- Medicine
- Brazilian journal of otorhinolaryngology
- 2020
Spanish Validation for Olfactory Function Testing Using the Sniffin’ Sticks Olfactory Test: Threshold, Discrimination, and Identification
- Medicine
- Brain sciences
- 2020
- 1
- PDF
Perspectives on the Intracellular Bacterium Chlamydia pneumoniae in Late-Onset Dementia
- Medicine
- Current Clinical Microbiology Reports
- 2020
- PDF
The association of frailty with olfactory and gustatory dysfunction in older adults: a nationally representative sample
- Medicine
- International forum of allergy & rhinology
- 2020
References
SHOWING 1-10 OF 292 REFERENCES
Progressive signaling changes in the olfactory nerve of patients with Alzheimer's disease
- Medicine
- Neurobiology of Aging
- 2019
- 9
- PDF
Olfactory dysfunction: common in later life and early warning of neurodegenerative disease.
- Medicine
- Deutsches Arzteblatt international
- 2013
- 76
Olfaction in patients with mild cognitive impairment and Alzheimer's disease
- Psychology, Medicine
- Neurobiology of Aging
- 2008
- 251
Axonal loss from the olfactory tracts in alzheimer's disease
- Biology, Medicine
- Neurobiology of Aging
- 1993
- 55
Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders
- Medicine
- Acta Neuropathologica
- 2011
- 78
Olfactory Dysfunction Correlates with Amyloid-β Burden in an Alzheimer's Disease Mouse Model
- Psychology, Medicine
- The Journal of Neuroscience
- 2010
- 217
- PDF
Awareness of olfactory deficits in healthy aging, amnestic mild cognitive impairment and Alzheimer's disease
- Medicine, Psychology
- International Psychogeriatrics
- 2011
- 47
Early Olfactory Involvement in Alzheimer’s Disease
- Medicine, Philosophy
- Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- 2003
- 143
- PDF
Immunohistochemical, volumetric, and functional neuroimaging studies in patients with idiopathic Parkinson's disease
- Psychology, Medicine
- Journal of the Neurological Sciences
- 2010
- 56