Olfaction in Three Genetic and Two MPTP-Induced Parkinson’s Disease Mouse Models

@inproceedings{Kurtenbach2013OlfactionIT,
  title={Olfaction in Three Genetic and Two MPTP-Induced Parkinson’s Disease Mouse Models},
  author={S. Kurtenbach and Sonja Wewering and H. Hatt and Eva M Neuhaus and Hermann Luebbert},
  booktitle={PloS one},
  year={2013}
}
Various genetic or toxin-induced mouse models are frequently used for investigation of early PD pathology. Although olfactory impairment is known to precede motor symptoms by years, it is not known whether it is caused by impairments in the brain, the olfactory epithelium, or both. In this study, we investigated the olfactory function in three genetic Parkinson's disease (PD) mouse models and mice treated with MPTP intraperitoneally and intranasally. To investigate olfactory function, we… CONTINUE READING

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