Oleic acid and linoleic acid are the major determinants of changes in keratinocyte plasma membrane viscosity.

@article{Dunham1996OleicAA,
  title={Oleic acid and linoleic acid are the major determinants of changes in keratinocyte plasma membrane viscosity.},
  author={William R. Dunham and Susan B Klein and Lenore M Rhodes and Cynthia Luz Marcelo},
  journal={The Journal of investigative dermatology},
  year={1996},
  volume={107 3},
  pages={332-5}
}
Keratinocytes were grown in medium with no essential fatty acids as well as in media with specially selected fatty acid augmentations. Gas chromatographic determinations of 21 fatty acids in the phospholipids were correlated with plasma membrane viscosity obtained by electron paramagnetic resonance studies (n = 24). Using standard procedures from multivariate analysis, we derived an expression that modeled the viscosity data as a function of four key fatty acid levels: [formula see text] where… CONTINUE READING

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