Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells

@inproceedings{Lamers2011OleicAA,
  title={Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells},
  author={Daniela Lamers and Raphaela Schlich and Sabrina Greulich and Shlomo Sasson and Henrike Sell and J{\"u}rgen Eckel},
  booktitle={Journal of cellular and molecular medicine},
  year={2011}
}
In the context of obesity, perivascular fat produces various adipokines and releases free fatty acids, which may induce inflammation and proliferation in the vascular wall. In this study we investigated how adipokines, oleic acid (OA) and the combined treatment regulate human vascular smooth muscle cell (hVSMC) proliferation and migration and the underlying signalling pathways. Adipocyte-conditioned media (CM) generated from human adipocytes induces a prominent proliferation and migration of… CONTINUE READING
29 Citations
48 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…