Oleate stimulates the formation of triglyceride-rich particles containing apoB100-apo(a) in long-term primary cultures of human hepatocytes.

@article{Edelstein1994OleateST,
  title={Oleate stimulates the formation of triglyceride-rich particles containing apoB100-apo(a) in long-term primary cultures of human hepatocytes.},
  author={Celina Edelstein and Nicholas O. Davidson and Angelo M. Scanu},
  journal={Chemistry and physics of lipids},
  year={1994},
  volume={67-68},
  pages={135-43}
}
Hepatocytes prepared from normal human liver donors were maintained in a synthetic, nutritionally defined, serum-free medium for up to 60 days with continuous secretion of the major plasma lipoproteins. By Western blot analysis, both cell lysates and culture media contained apo(a), both unbound and bound to apo B100, in varying proportions, dependent on the… CONTINUE READING