Oleanolic acid and hederagenin glycosides from Weigela stelzneri.

@article{Rezgui2016OleanolicAA,
  title={Oleanolic acid and hederagenin glycosides from Weigela stelzneri.},
  author={Abdelmalek Rezgui and Anne-Claire Mitaine-Offer and Tomofumi Miyamoto and Chiaki Tanaka and St{\'e}phanie Delemasure and Patrick Dutartre and Marie‐Aleth Lacaille‐Dubois},
  journal={Phytochemistry},
  year={2016},
  volume={123},
  pages={
          40-7
        }
}

Phytochemistry of Weigela x “kosteriana variegata” (Caprifoliaceae)

One new triterpene glycoside 3-O-β-D-xylopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→3)]-β-D-xylopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyloleanolic acid, was

New triterpenoid saponin glycosides from the fruit fibers of Trichosanthes cucumerina L.

Five new triterpenoid saponin glycosides, trichocucumerisides A–E (1–5), together with eleven known compounds (6–16) were isolated from Trichosanthes cucumerina fruit fibers. The structures of the

ISOLATION OF TRITERPENOID SAPONINS FROM THE LEAVES OF WEIGELA X “BRISTOL RUBY”

Received: 06/02/2022 Weigela genus of Asparagaceae family contains 10 species which are distributed mainly in Asia region, however, there are more than 200 species which have been cultivated for many

References

SHOWING 1-10 OF 13 REFERENCES

Triterpene glycosides with stimulatory activity on melanogenesis from the aerial parts of Weigela subsessilis

TLDR
Three new triterpene glycosides (Lonicerosides K, L and M) and 11 known compounds were isolated from the aerial parts of Weigela subsessilis and had potent melanogenesis stimulatory activity in murine B16F0 melanoma cells.

Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship.

TLDR
Two saponins isolated from the root of Pulsatilla koreana were examined for their in vitro cytotoxic activity against the human solid cancer cell lines and in vivo antitumor activity, suggesting that the two elements are essential factors for the antitumors activity.

New biologically active triterpenoid saponins from Scabiosa tschiliensis.

TLDR
Eleven new triterpenoid saponins, scabiosaponins A-K, and hookerosides A, B, and prosapogenin 1b were isolated from the whole plants of Scabiosa tschiliensis and exhibited strong inhibition of pancreatic lipase in vitro.

Cytotoxic triterpenoid saponins from the rhizomes of Anemone taipaiensis.

TLDR
Six saponins, 1, 2, 4- 7, which possessed a free carboxylic group at C-28, exhibited significant cytotoxicity against human leukemia HL-60 cells and human hepatocellular carcinoma Hep-G2 cells with IC (50) values in the range of 1.31-10.12 µM.

Gas-liquid chromatographic separation of aldose enantiomers as trimethylsilyl ethers of methyl 2-(polyhydroxyalkyl)thiazolidine-4(R)-carboxylates

Pairs of enantiomers of nine aldoses were separated by gas-liquid chromatography on an OV-17 capillary column as the trimethylsilyl ethers of methyl 2- (polyhydroxyalkyl) -thiazolidine-4 (R)

Cryopyrin activates the inflammasome in response to toxins and ATP

TLDR
It is shown that cryopyrin-deficient macrophages cannot activate caspase-1 in response to Toll-like receptor agonists plus ATP, the latter activating the P2X7 receptor to decrease intracellular K+ levels.

Why not treat human cancer with interleukin-1 blockade?

  • C. Dinarello
  • Biology, Medicine
    Cancer and Metastasis Reviews
  • 2010
TLDR
Clinical trials of interleukin-1 blockade should be initiated, particularly as an add-on therapy of patients receiving antiangiogenesis-based therapies, given the availability of three therapeutic agents for limiting IL-1 activity, the safety of blockingIL-1, and the clear benefit of blocking IL- 1 activity in animal models of metastasis and angiogenesis.

Cancer-related inflammation

TLDR
The molecular pathways of this cancer-related inflammation are now being unravelled, resulting in the identification of new target molecules that could lead to improved diagnosis and treatment.