Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro

@inproceedings{Dionisi2012OleamideAP,
  title={Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro},
  author={Mauro Dionisi and Stephen P. H. Alexander and Andrew J. Bennett},
  booktitle={Lipids in Health and Disease},
  year={2012}
}
Oleamide (ODA) is a fatty acid primary amide first identified in the cerebrospinal fluid of sleep-deprived cats, which exerts effects on vascular and neuronal tissues, with a variety of molecular targets including cannabinoid receptors and gap junctions. It has recently been reported to exert a hypolipidemic effect in hamsters. Here, we have investigated the nuclear receptor family of peroxisome proliferator-activated receptors (PPARs) as potential targets for ODA action. Activation of PPAR… CONTINUE READING

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