Older asymptomatic women exhibit patterns of thumb carpometacarpal joint space narrowing that precede changes associated with early osteoarthritis.

@article{Halilaj2015OlderAW,
  title={Older asymptomatic women exhibit patterns of thumb carpometacarpal joint space narrowing that precede changes associated with early osteoarthritis.},
  author={Eni Halilaj and Douglas C. Moore and Tarpit K. Patel and David H. Laidlaw and Amy L. Ladd and Arnold-Peter C. Weiss and Joseph J. Crisco},
  journal={Journal of biomechanics},
  year={2015},
  volume={48 13},
  pages={3634-40}
}
In small joints, where cartilage is difficult to image and quantify directly, three-dimensional joint space measures can be used to gain insight into potential joint pathomechanics. Since the female sex and older age are risk factors for carpometacarpal (CMC) joint osteoarthritis (OA), the purpose of this in vivo computed tomography (CT) study was to determine if there are any differences with sex, age, and early OA in the CMC joint space. The thumbs of 66 healthy subjects and 81 patients with… CONTINUE READING