Older age of rheumatoid arthritis onset is associated with higher activation status of peripheral blood CD4(+) T cells and disease activity.

@article{Pawowska2011OlderAO,
  title={Older age of rheumatoid arthritis onset is associated with higher activation status of peripheral blood CD4(+) T cells and disease activity.},
  author={Justyna Pawłowska and Żaneta Smoleńska and Agnieszka Daca and Jacek M. Witkowski and Ewa M Bryl},
  journal={Clinical and experimental immunology},
  year={2011},
  volume={163 2},
  pages={157-64}
}
Rheumatoid arthritis (RA) is a chronic inflammatory disease, with a clinical manifestation both systemic and in joints. It has been suggested that age at disease onset and/or patients' age have influence on disease activity and clinical outcome. The reasons for the different course of RA in older people are not known; however, the activation status of peripheral blood lymphocytes could be responsible. Our aim was to relate expression of activation markers in peripheral blood CD4(+) T cells of… CONTINUE READING