Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinations.

Abstract

Since the 23-valent pneumococcal polysaccharide vaccine (PPV23) is less effective for older adults than for young adults, it is important to investigate the immunologic basis for the reduced efficacy of PPV23 among older adults. We determined the effectiveness of PPV23 among young (n = 55) and older (n = 44) adults by measuring the serum IgG, IgM, and IgA… (More)
DOI: 10.1128/IAI.00768-10

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Cite this paper

@article{Park2011OlderAH, title={Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinations.}, author={Saeyoung Park and Moon H. Nahm}, journal={Infection and immunity}, year={2011}, volume={79 1}, pages={314-20} }