Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life

@article{Curran2003OlderAA,
  title={Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life},
  author={H. Val Curran and Ruth Harvey Collins and Susan L. Fletcher and S Kee and B Woods and Steve Iliffe},
  journal={Psychological Medicine},
  year={2003},
  volume={33},
  pages={1223 - 1237}
}
Background. Older adults are the main recipients of repeat prescriptions for benzodiazepine (BZD) hypnotics. BZDs can impair cognitive function and may not aid sleep when taken continuously for years. This study therefore aimed to determine if withdrawing from BZDs leads to changes in patients' cognitive function, quality of life, mood and sleep. Method. One hundred and ninety-two long-term users of BZD hypnotics, aged [ges ]65 years, were identified in 25 general practices. One hundred and… 
Attitudes to long-term use of benzodiazepine hypnotics by older people in general practice: findings from interviews with service users and providers
TLDR
Patients and doctors had distinctly different views of the advantages, disadvantages and risks of stopping benzodiazepine hypnotic use, and an evidence-based approach to withdrawal efforts in primary care are necessary to reduce the consumption of medication that has little real benefit.
Effect of withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotic agents on cognition in older adults
TLDR
Long-term use of BDZ as hypnotic drugs by older adults is related to prolonged impairment of attentional and psychomotor cognitive functioning that persists for at least 6 months after withdrawal.
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TLDR
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TLDR
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TLDR
The persistence of temazepam, zolpidem, and zopiclone (BZDA) withdrawal among older outpatients at 3 years from the beginning of withdrawal is described, as well as any changes in use of other medications.
Long-term persistence of withdrawal of temazepam, zopiclone, and zolpidem in older adults: a 3-year follow-up study
TLDR
The persistence of temazepam, zolpidem, and zopiclone (BZDA) withdrawal among older outpatients at 3 years from the beginning of withdrawal is described, as well as any changes in use of other medications.
Withdrawing Benzodiazepines in Primary Care
TLDR
The clearest strategy was to taper the medication; abrupt cessation can only be justified if a very serious adverse effect supervenes during treatment, and no clear evidence suggests the optimum rate of tapering, and schedules vary from 4 weeks to several years.
Analysis of benzodiazepine withdrawal program managed by primary care nurses in Spain
TLDR
A nurse-led BZD withdrawal program adapted to Spanish Primary Care working conditions showed an overall improvement in depression and anxiety scales, and in the mental component of the quality of life scale.
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