Old Acetogens, New Light

@article{Drake2008OldAN,
  title={Old Acetogens, New Light},
  author={Harold L Drake and Anita S. Gö{\ss}ner and Steven L. Daniel},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1125}
}
Acetogens utilize the acetyl‐CoA Wood‐Ljungdahl pathway as a terminal electron‐accepting, energy‐conserving, CO2‐fixing process. The decades of research to resolve the enzymology of this pathway (1) preceded studies demonstrating that acetogens not only harbor a novel CO2‐fixing pathway, but are also ecologically important, and (2) overshadowed the novel microbiological discoveries of acetogens and acetogenesis. The first acetogen to be isolated, Clostridium aceticum, was reported by Klaas… 
Enzymology of the Wood–Ljungdahl Pathway of Acetogenesis
  • S. Ragsdale
  • Biology, Medicine
    Annals of the New York Academy of Sciences
  • 2008
The biochemistry of acetogenesis is reviewed. The microbes that catalyze the reactions that are central to acetogenesis are described and the focus is on the enzymology of the process. These microbes
Formate-Dependent Acetogenic Utilization of Glucose by the Fecal Acetogen Clostridium bovifaecis
TLDR
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TLDR
This review provides a short history of the important discoveries that have led to the identification of the key components and steps of this usual mechanism of CO and CO(2) fixation and describes the properties of the genes and enzymes involved in the pathway.
Energy conservation under extreme energy limitation: the role of cytochromes and quinones in acetogenic bacteria
TLDR
The literature on the characterization of cytochromes and quinones in acetogens are reviewed and a hypothesis that they may function in electron transport chains in addition to Rnf and Ech is presented.
Older Than Genes: The Acetyl CoA Pathway and Origins
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    Frontiers in Microbiology
  • 2020
TLDR
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TLDR
A novel, Sporomusa type Nfn (Stn), built from existing modules of enzymes such as the soluble [Fe–Fe] hydrogenase, that is widespread in acetogens and other anaerobic bacteria is identified.
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TLDR
The energetic advantages of coupling CO2 reduction to fermentations that exploit otherwise-inaccessible substrates and the ecological advantages, as well as the biotechnological applications of the heterotrophic metabolism of acetogens are discussed.
Energy Conservation in the Acetogenic Bacterium Clostridium aceticum
TLDR
Experimental data and in silico analyses enabled us to propose the biochemistry and bioenergetics of acetogenesis from H2 + CO2 in C. aceticum, and it is proposed that this organism contains cytochromes and therefore may use a proton gradient in its respiratory chain.
The defining genomic and predicted metabolic features of the Acetobacterium genus
TLDR
The findings suggest that outside of the reductive acetyl-CoA (Wood-Ljungdahl) pathway, the Acetobacterium genus is more phylogenetically and metabolically diverse than expected, with metabolism of fructose, lactate, and H2:CO2 constant across the genus, and ethanol, methanol, caffeates, and 2,3-butanediol varying across the species.
Acetogens: Biochemistry, Bioenergetics, Genetics, and Biotechnological Potential
The review discusses the present-day data on the biochemistry, bioenergetics, and genetics of acetogens, as well as their biotechnological potential. Acetogens are anaerobic gram-positive bacteria
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TLDR
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TLDR
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