Olaparib treatment for BRCA-mutant ovarian cancer with leptomeningeal disease

@inproceedings{Bangham2016OlaparibTF,
  title={Olaparib treatment for BRCA-mutant ovarian cancer with leptomeningeal disease},
  author={Madeleine Bangham and Robert Goldstein and Henry Walton and Jonathan A Ledermann},
  booktitle={Gynecologic oncology reports},
  year={2016}
}
•Leptomeningeal disease occurs more commonly in BRCA-mutated ovarian cancer.•A clinically significant dose of olaprib is able to penetrate the leptomeninges.•Leptomeningeal metastases in a BRCA-mutated ovarian cancer responded to olaparib. 
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