Olanzapine versus haloperidol in the treatment of agitation in elderly patients with dementia: results of a randomized controlled double-blind trial.

@article{Verhey2006OlanzapineVH,
  title={Olanzapine versus haloperidol in the treatment of agitation in elderly patients with dementia: results of a randomized controlled double-blind trial.},
  author={Frans R. J. Verhey and Mike Verkaaik and Richel H. B. Lousberg},
  journal={Dementia and geriatric cognitive disorders},
  year={2006},
  volume={21 1},
  pages={1-8}
}
The goal of this study was to compare the efficacy and safety of olanzapine versus haloperidol in the treatment of agitation and aggression in patients with dementia. The subjects were 58 out-patients with dementia and agitation. After baseline assessments and, if necessary, a period of wash-out of a previous antipsychotic drug, they were randomly assigned to 5 weeks of double-blind treatment with either olanzapine or haloperidol. The first 2 weeks were used for dose titration. Subsequently… CONTINUE READING

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