Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group.

@article{Street2000OlanzapineTO,
  title={Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group.},
  author={Jewry Street and W. Scott Clark and Kimberly S. Gannon and Jeffery L Cummings and Frank P. Bymaster and Roy N Tamura and Steven J Mitan and Deborah L Kadam and Todd M Sanger and Peter D. Feldman and Gary D. Tollefson and Alan Breier},
  journal={Archives of general psychiatry},
  year={2000},
  volume={57 10},
  pages={968-76}
}
BACKGROUND Patients with Alzheimer disease (AD) commonly exhibit psychosis and behavioral disturbances that impair patient functioning, create caregiver distress, and lead to institutionalization. This study was conducted to assess the efficacy and safety of olanzapine in treating psychosis and/or agitation/aggression in patients with AD. METHODS A multicenter, double-blind, placebo-controlled, 6-week study was conducted in 206 elderly US nursing home residents with AD who exhibited psychotic… CONTINUE READING
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A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia

  • PP De Deyn, K Rabheru, +4 authors BA. Lawlor
  • Neurology
  • 1999
1 Excerpt

Kowalcyk BB, and the Seroquel Trial 48 Study Group. Quetiapine, a novel antipsychotic: experience in elderly patients with psychotic disorders

  • DQ McManus, LA Arvanitis
  • J Clin Psychiatry
  • 1999
1 Excerpt

Review of the preclinical pharmacology of olanzapine: a MARTA class antipsychotic

  • FP Bymaster, NA Moore, T. Nakazawa
  • Jpn J Clin Psychopharmacol
  • 1999

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